Benazepril kuzinja namakati

I-Benazepril, eyaziwa nangokuthi Fortekor® noLotensin®, isetshenziselwa inja nekati njalo. Inemisebenzi eminingi, kuhlanganise nokuphatha inhliziyo nenkinga yezinso kokubili i-canine ne-feline.

I-Benazepril iyingxenye yeklasi yezidakamizwa ezaziwa ngokuthi ama-inhibitors e-angiotensin-abaguqula i-enzyme noma ama-inhibitors e-ACE. Umthelela wabo oyinhloko yi-vasodilation (ukuhanjiswa kwemithambo yegazi).

Yini Inhibitha E-ACE Efana ne-Benazepril Ingabe Inja Nekati?

I-enzyme yokuguqula ama-angiotensin (ACE) iyingxenye yesistimu emzimbeni okhiqiza isakhi esaziwa nge-angiotensin-ll.

I-Angiotensin-i-vasoconstrictor enamandla, okusho ukuthi inciphisa imithwalo yegazi emzimbeni wonke. Lokhu kuncibilika kwemithambo yegazi kubangela ukumelana okwandayo ngaphakathi kwemikhumbi, okwakwandisa inani lomsebenzi inhliziyo okufanele iyenze ukupompa igazi emifuleni yegazi.

Uma i-benazepril inikezwa inja noma ikati, ivimbela i-enzyme yokuguqula i-angiotensin, okuholela ekukhiqizeni okungezansi kwe-angiotensin. Amazinga aphansi e-angiotensin-ll, nawo, aholela ekwenzeni i-vasodilation, ukwanda kwamanani emithwalo yegazi etholakala kuwo wonke umzimba. Lokhu kunemiphumela eminingana:

• I-Benazepril idala ngokuphumelelayo i-vasodilation, okwenza kube lula ngenhliziyo ukupompa igazi ngokusebenzisa izitsha nakuwo wonke umzimba. Lena yindlela ephumelelayo yokuthatha okunye komthwalo osuka enhliziyweni.
• I-Benazepril nayo isiza ukunciphisa ukucindezelwa kwegazi ngokubangela ukuguqulwa kwegazi.
• Ngaphezu kwalokho, i-benazepril ikwandisa ukugeleza kwegazi ezintsheni, okunye kwezinye izilwane ezinesifo sezinso ezingasiza izinso ukuba zisebenze ngokuphumelelayo.

Ukusetshenziswa kwe-Benazepril kuzinja namakati

I-Benazepril, ngenxa yesenzo sayo njenge-vasodilator, isetshenziselwa ukuphatha ukwehluleka kwenhliziyo yezinhlanzi kokubili izinja namakati. Ezimweni eziningi, i-benazepril isetshenziswa kanye ne-furosemide (Lasix®). Uma lezi zidakamizwa ezimbili zihlanganisiwe, izinga lokuphila inja noma ikati ekuhlukunyekeni kwenhliziyo kungathuthukiswa kakhulu ezimweni eziningi.

Kubalulekile ukuthi uqaphele ukuthi umthamo we-furosemide ungadinga ukunciphisa ukuze umfutho wegazi wesilwane sakho ungabi phansi kakhulu.

I-Benazepril isetshenziselwa ukwelapha isifo se- canine ne-feline yezinso , ukuhluleka okungenangqondo kwezinso (impumulo) nezinso zezinso lapho inani elingaphansi lamaprotheni lihlungwa phakathi kwezinso kanye nomchamo (amaprotheni-alahlekelwa yi-nephropathies.)

Ngezinye izikhathi i-Benazepril isetshenziselwa ukuphatha umfutho wegazi ophezulu ezinja nasekamakati.

Imiphumela emibi yokubuka kuzinja nezinja ezithola i-Benazepril

Imiphumela emibi kakhulu evame ukukhushulwa kwamathumbu njengokuhlanza, isifo sohudo, ukungabi nesifiso sokudla kanye nobuthakathaka. Kodwa-ke, imiphumela emibi kakhulu efana ne-hypotension (i-low blood pressure), izinga eliphezulu le-potassium legazi (hyperkalemia) kanye nokulimala kwezinso nakho kungenzeka. Izinja namakati athola i-benazepril kufanele ihlolwe eduze ekhaya futhi kufanele ihlolwe ngezikhathi ezithile yi-veterinarian yabo.

I-Benazepril yaziwa ukudlulisa i-placenta kunoma yikuphi ukukhula kokubeletha. Uma usebenzisa i-benazepril ezilwaneni ezikhulelwe , izinzuzo zokusetshenziswa kwazo kufanele zilinganiswe nezingozi zokulahlekelwa noma ukulimaza izinsana noma amazinyane angakazalwa.

I-Benazepril (Fortekor®, i-Lotensin®) ezinja kanye namakati iphumelela ekwelapheni ukuhluleka kwenhliziyo futhi isetshenziselwa ukwelapha isifo sezinso kanye nomfutho wegazi ophezulu (umfutho wegazi ophezulu.)